Metastatic brain carcinomas
Conditions
Interventions
Sponsors
The First Affiliated Hospital of Chengdu Medical College
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) Age =18 years old, gender unlimited; 2) Histologically confirmed solid malignant tumor at the primary site or metastatic site; 3) Imaging confirmed 5mm extra-marginal brain metastases around the hippocampus (1-3 lesions) (the maximum diameter of a single lesion is 5cm, and the maximum diameter of multiple lesions is not more than 3cm); 4) ECOG score of 0-2, life expectancy of at least 6 months; 5) Not pregnant or breastfeeding; 6) The subject must understand and sign the informed consent 7) Have reading comprehension ability and can complete the questionnaire with medical assistance; 8) Those who voluntarily participate in the study and sign the informed consent letter in person
Exclusion criteria
Exclusion criteria: 1) Previously received craniocerebral radiation therapy; 2) Diffuse meningeal metastasis; 3) Have a mental illness that the investigator believes will interfere with completion of treatment or follow-up; 4) Unable to perform enhanced MRI; 5) Patients with severe underlying diseases who cannot tolerate radiotherapy; 6) Tumor PTV volume > 60cc; 7) The patient was diagnosed with primary brain tumor and primary germ cell tumor; 8) Female patients who are pregnant or breastfeeding; 9) Other cases deemed unsuitable for inclusion by the investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time of intracranial lesion progression; | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in cognitive function and quality of life;Adverse effects; | — |
Countries
China
Contacts
Public ContactTao Ren
The First Affiliated Hospital of Chengdu Medical College
Outcome results
None listed