Uterine fibroids
Conditions
Interventions
Oxytocin intervention group:Intramuscular injection of oxytocin at different concentrations
Normal saline control group:Normal saline intramuscular injection
Sponsors
Jiaxing Maternal and Child Health Hospital
Eligibility
Sex/Gender
Female
Age
20 Years to 55 Years
Inclusion criteria
Inclusion criteria: Age 20 to 55 years, Ultrasound or magnetic resonance diagnosis of intermural leiomyomas (mainly type V (fibroids that penetrate the entire myometrium) and type VI (fibroids that protrude into the serosa) Fibroid excision is clinically indicated Elective laparoscopic myomectomy under general anesthesia.
Exclusion criteria
Exclusion criteria: Patients with moderate to severe anemia before surgery Previous myomectomy History of preoperative hormonal therapy Pregnant and postmenopausal women Obesity (body mass index >30 kg/m^2) The maximum diameter of a single >10 cm Major organ or systemic diseases (e.g., ischemic heart disease, congestive heart failure, cerebrovascular disease, renal vascular disease, hypertension, etc.) Severe intra-abdominal adhesions
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the amount of blood lost;Changes in hemoglobin before and after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of surgery;The surgeon's rating of satisfaction with the procedure;Intraoperative blood pressure;Heart rate during surgery;Number of days in hospital; | — |
Countries
China
Contacts
Public ContactZepeng Ping
Jiaxing Maternal and Child Health Hospital
Outcome results
None listed