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Efficacy of Antidepressants Combined with Transcranial Alternating Current Stimulation in Adolescents with Depression

Efficacy of Antidepressants Combined with Transcranial Alternating Current Stimulation in Adolescents with Depression

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400084251
Enrollment
Unknown
Registered
2024-05-13
Start date
2023-11-01
Completion date
Unknown
Last updated
2024-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

depression

Interventions

intervention group:On the basis of using antidepressants (mainly SSRIs drugs), the patient was treated with a frequency of 77.5Hz and a current of 15mA of tACS,twice a day (5 days per week for 2 cons
Control group:antidepressants (mainly SSRIs drugs)

Sponsors

The First Affiliated Hospital of Chongqing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
12 Years to 17 Years

Inclusion criteria

Inclusion criteria: 1. Aged 12-17 years old, seeking medical treatment in our outpatient and inpatient wards; 2. According to the diagnostic criteria of DSM-5 for "major depressive disorder" and evaluated by at least one professional psychiatrist 3. Compliant with the Hamilton Depression Scale with a score of = 21; 4. Capable of understanding the questionnaire content and answering it in practice; 5. Voluntarily participate in the project and have a guardian sign an informed consent form

Exclusion criteria

Exclusion criteria: 1. Individuals with comorbidities and other mental disorders; 2. Individuals with severe physical and neurological disorders; 3. Existence of substance abuse or dependence; 4. Damaged skin integrity at the electrode placement site; 5. Equipped with implanted electronic devices; 6. Those who cannot complete the evaluation without cooperation/refuse to complete the 4-week clinical follow-up.

Design outcomes

Primary

MeasureTime frame
Hamilton Depression Scale;Hamilton Anxiety Scale;

Secondary

MeasureTime frame
Beck Suicide Intention Scale;Self Rating Depression Symptom Scale;Generalized Anxiety Disorder Scale;

Countries

China

Contacts

Public ContactKuang Li

The First Affiliated Hospital of Chongqing Medical University

kuangli0308@163.com+86 139 0837 9733

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026