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Effect of ventilation during extubation on atelectasis after laparoscopic gynaecological surgery with the steep Trendelenburg position: a randomized controlled trial

Effect of ventilation during extubation on atelectasis after laparoscopic gynaecological surgery with the steep Trendelenburg position: a randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400084235
Enrollment
Unknown
Registered
2024-05-13
Start date
2024-06-01
Completion date
Unknown
Last updated
2024-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

laparoscopic gynaecological surgery with the steep Trendelenburg position

Interventions

SIMV-PCV-VG group:SIMV-PCV-VG mode would be implemented during anesthetic emergence
PSVpro group:PSVpro mode would be implemented during anesthetic emergence

Sponsors

West China Second Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Eligible participants include adults (18 years = Age<80 years) with an ASA physical status of I to III, scheduled for elective laparoscopic gynecological surgery requiring steep Trendelenburg positioning, and having an expected surgical duration exceeding two hours, with planned extubation in the operating room.

Exclusion criteria

Exclusion criteria: Exclusion criteria encompass a recent history (within three months) of pneumothorax, acute lung injury, or acute respiratory distress syndrome; uncontrolled asthma; previous lung surgery; moderate or severe obstruction observed on pulmonary function test; chest x-ray anomalies such as atelectasis, pneumothorax, or giant bullae; expectation of difficult intubation (Mallampati class 3 or 4), pregnancy, and patient’s refusal.

Design outcomes

Primary

MeasureTime frame
the incidence of postoperative atelectasis;

Secondary

MeasureTime frame
LU scores;incidence of desaturation;needed supplemental oxygen;Pain score;Postoperative pulmonary complications before discharge ;Event of reintubation;Unplanned admission to ICU;Postoperative hospital stay;

Countries

China

Contacts

Public ContactDongxu Chen

West China Second Hospital, Sichuan University

scucdx@foxmail.com+86 158 8173 0901

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026