allergic rhinitis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. 5 years = age =65 years 2. IgE mediated allergic rhinitis with or without allergic asthma caused by house dust mite allergens (house dust mites and/or dust mites) 3. If accompanied by bronchial asthma, ensure that their asthma symptoms are well controlled according to GINA 2020 guidelines 4. Received AIT treatment
Exclusion criteria
Exclusion criteria: 1. In the judgment of the investigator, the subject and/or parent/legal guardian are unable to understand and comply with the requirements of the study 2. Patients with severe or uncontrolled asthma (FEV1 <70% predicted value) and irreversible airflow obstruction 3. Patients on beta-blockers or Angiotensin-converting enzyme (ACE) inhibitors 4. Severe autoimmune diseases, including AIDS, inflammatory bowel disease and other immune deficiency diseases and autoimmune diseases, as well as active infection, diabetes, gastric ulcer and other patients 5. Patients with severe psychological disorders or those that can not accept the risk of treatment 6. Suffering from severe cardiovascular disease 7. Cancer 8. pregnancy 9. Poor compliance
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin Prick Tests(SPT);serum IgE;VAS score;Symptom score;Drug scores;AEs information;Emerging Allergens;New-onset asthma; | — |
Countries
China
Contacts
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology