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Efficacy of fMRI-guided individualized dACC/pre-SMA target-based iTBS on semantic processing functions and brain remodeling mechanisms in normal humans

Efficacy of fMRI-guided individualized dACC/pre-SMA target-based iTBS on semantic processing functions and brain remodeling mechanisms in normal humans

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400084225
Enrollment
Unknown
Registered
2024-05-13
Start date
2024-05-20
Completion date
Unknown
Last updated
2024-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

none

Interventions

iTBS Group:iTBS treatment
sham Group:sham intervention

Sponsors

Wuxi Mental Health Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: 1. Age: 18-35 years old; 2. Right-handed; 3. Native Chinese speaker; 4. Normal or corrected vision and normal hearing; 5. MMSE score of 28 or above

Exclusion criteria

Exclusion criteria: 1. Patients with contraindications related to TMS (cardiac pacemaker, intracranial implant, implanted drug pump or pregnancy, etc.); 2. Past neuropsychological illness (depression, anxiety, schizophrenia, etc.); 3. Patients with cognitive or communication disabilities; 4. Currently participating in other TMS trials.

Design outcomes

Primary

MeasureTime frame
Event-related potential N400;—

Secondary

MeasureTime frame
MRI;Indicators related to computer tasks;The Pittsburgh Sleepiness Scale;—

Countries

China

Contacts

Public ContactRen Caili

Wuxi Mental Health Center

sally7226@163.com+86 153 0617 5051

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026