gastrointestinal tumors
Conditions
Interventions
the control group:In the control group, patients received essential health education (healthy diets and other precautions), and a regular diet (without the use of Ayunutri).
the enteral ecoimmunonutrition group:In the EIN group, besides regular diet, patients were administered orally a jar (237 mL) of Ayunutri from the first day of chemotherapy for 42 days.
Sponsors
Hebei General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: ? with a diagnosis of esophageal, gastric, or colorectal cancer confirmed by surgical/endoscopic pathology; ? the cancer was radiologically assessed as stage III or IV according to the American Joint Committee on Cancer (AJCC) staging manual (8th edition), along with the presence of assessable lesions; ? the patient could be fed orally; ? with an expected survival of =3 months; ?requiring systemic chemotherapy (biweekly or three-weekly combination chemotherapy regimens); and ? aged 18 - 80 years (including 18 and 80 years).
Exclusion criteria
Exclusion criteria: ?with co-existing hepatic and renal insufficiency and other metabolic diseases that could not be controlled by medications; ? with acute or chronic infections at other sites; ?use of steroids or immunosuppressive agents; ? with accompanying malignant tumors; ? with complete intestinal obstruction; ? could not be fed orally; and? allergic to the study drug or unable to complete the study due to other reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| assessment of the nutritional risk;assessment of the nutritional status; | — |
Secondary
| Measure | Time frame |
|---|---|
| assessment of the quality of life ;assessment of the chemotherapy toxicities; | — |
Countries
China
Contacts
Public ContactJia Yitao
Hebei General Hospital
Outcome results
None listed