HIV/AIDS
Conditions
Interventions
TFV Group:None
3TC group:None
Sponsors
Beijing Ditan Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1)Age 18-65 years old, male or female, with positive HIV confirmatory test (2) HIV antiretroviral treatment-experienced patients who have been on treatment for more than half a year and whose HIV viral load is consistently less than 50copies/ml, and whose initial treatment regimen is a TFV-containing regimen, and who have been stably converted to a 3TC-based dual regimen. 3)Hepatitis B test results and HBcAb positive/HBsAg negative before the initial treatment. (4) Voluntarily sign the informed consent and willing to participate in the study.
Exclusion criteria
Exclusion criteria: 1) Those with co-morbid opportunistic infections were not included in the study; 2) Those planning pregnancy were not included in the study; 3) Those with severe hepatic and renal impairment were not included in the study. (4) HBsAg-positive persons were not included in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HBV DNA; | — |
Secondary
| Measure | Time frame |
|---|---|
| HIV RNA;Liver function;Liver ultrasound;CD4 and CD8 counts; | — |
Countries
China
Contacts
Public ContactHongxin Zhao
Ditan hospital,Peking,China
Outcome results
None listed