Erection dysfunction, ED
Conditions
Interventions
Group A(post radical prostatectomy: sexual nerves reserved, Group 1):3 times injection of the autologous adipose-derived SVF into the penile corpus cavernosum
Group B(post radical prostatectomy: sexual nerves reserved, Group 2):6 times injection of the autologous adipose-derived SVF into the penile corpus cavernosum
Group C(post radical prostatectomy: sexual nerves unreserved, Group 1):3 times injection of the autologous adipose-derived SVF into the penile corpus cavernosum
Group D (post radical prostatectomy: sexual nerves unreserved, Group 2):6 times injection of the autologous adipose-derived SVF into the penile corpus cavernosum
Group E (non-surgical origin, Group 1):3 times injection of the autologous adipose-derived SVF into the penile corpus cavernosum
Group F (non-surgical origin, Group 2):6 times injection of the autologous adipose-derived SVF into the penile corpus cavernosum
Sponsors
Beijing Anzhen Hospital, Capital Medical University
Eligibility
Sex/Gender
Male
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: a. Subject must participate and sign an informed Consent form Voluntarily, age must be at the range of 18-65 years old; b. Subject with clinically diagnosed with erectile dysfunction either caused by non-surgical origin, or post radical prostatectomy without distant metastasis; c. Subject had sexual activity before treatment and expressed a desire to remain sexually active; d. Subject had traditional treatmentss for erectile dysfunction, but the treatment were inefficacious; e. ECOG score is 0-1; f. Subject is generally in good condition and laboratory tests include, but are not limited to the following requirements: 1) Neutrophil absolute count =1.5×10^9/L, platelets =100×10^9/L, hemoglobin =90g/L 2) International Normalized Ratio(INR) or Activated Partial Thromboplastin Time(APTT) =1.5× upper limit of normal range 3) Urine routine leukocyte (-) g. Subject must use effective contraception during the study period.
Exclusion criteria
Exclusion criteria: a. Poor physical condition and unable to tolerate the treatment; b. Anticoagulant therapy is being appied or there is a clotting disorder; c. No sexual activity; d. Poorly controlled diabetes or there is a local inflammation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| International Index of Erectile Function(IIEF);Erection Hardness Score (EHS); | — |
Secondary
| Measure | Time frame |
|---|---|
| International Consultation on Incontinence Questionnaire-Urinary Incontinence Short Form (ICIQ-UI SF); | — |
Countries
China
Contacts
Public ContactBaoan Hong
Beijing Anzhen Hospital, Capital Medical University
Outcome results
None listed