postpartum depression
Conditions
Interventions
Sponsors
XuanCheng People's Hospital
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Aged 20–40 years. 2. American Society of Anesthesiologists class I-II. 3. Singleton full-term pregnancy. 4. Voluntarily to receive cesarean section and postoperative controlled analgesia. 5. Consented to participate in the study.
Exclusion criteria
Exclusion criteria: 1. History of diagnosed mental disorders, psychiatric medication, or psychotropic substance use at any time before. 2. History of neurological diseases such as epilepsy. 3. History of previously diagnosed depression. 4. With suicidal ideation or history of suicide. 5. History of drug, alcohol, or opioid abuse. 6. Monoamine oxidase inhibitor treatment at present or in the past 14 days. 7. Participating in other clinical studies. 8. With severe heart disease, brain disease, liver disease and kidney disease. 9. With any contraindication for CSEA. 10. Incapable of communication or cooperation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| incidence of postpartum depression at 4 weeks after the caesarean section ;norepinephrine levels at 48 hours postoperatively; | — |
Secondary
| Measure | Time frame |
|---|---|
| incidence of postpartum depression at 3 months after the caesarean delivery;EPDS scores at 4 weeks after the caesarean delivery;GAD-7 scores at 4 weeks after the caesarean delivery;EPDS scores at 3 months after the caesarean delivery;GAD-7 scores at 3months after the caesarean delivery;norepinephrine level before the surgery; | — |
Countries
China
Contacts
Public ContactKaiying Zhang
XuanCheng People's Hospital
Outcome results
None listed