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Effect of increasing mean arterial pressure on perioperative pulmonary edema in patients with hysteroscopic myomectomy

Effect of increasing mean arterial pressure on perioperative pulmonary edema in patients with hysteroscopic myomectomy

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400084177
Enrollment
Unknown
Registered
2024-05-11
Start date
2024-05-13
Completion date
Unknown
Last updated
2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pulmonary edema

Interventions

Phenylephrine group (P Group) :During the operation, the experimental drug was pumped continuously, the initial dose was 10ml/h, and the infusion speed of the experimental drug was adjusted to maintai
Control group:During the operation, 10ml/h of normal saline was pumped continuously

Sponsors

Obstetrics and Gynecology Hospital of Fudan University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: (1) Patients undergoing elective hysteroscopic type 2 or type 3 hysteromyomectomy under general anesthesia; (2) Age 18-60; (3) ASA I-II level; (4) The expected operation time is more than 30 minutes.

Exclusion criteria

Exclusion criteria: (1) Patients with BMI greater than 35kg/m2; (2) Pregnant or lactating patients; (3) Patients with a history of abnormal surgical anesthesia; (4) Patients with cardiovascular and cerebrovascular diseases, such as hypertension, coronary heart disease or cerebrovascular malformations; (5) The patient refuses the participant; (6) Patients with height less than 150cm; (7) Patients with body weight less than 45kg; (8) Patients with cardiopulmonary insufficiency.

Design outcomes

Primary

MeasureTime frame
Occurrence of pulmonary edema;

Secondary

MeasureTime frame
Pulmonary ultrasound B line score;Hemodynamic parameters of TEB;Loss of Distention fluid;Electrolytes, Hemoglobin and HCT in blood gas analysis;Surgical visual field clarity score;Blood loss;Adverse event;

Countries

China

Contacts

Public ContactJiawei Chen

Obstetrics and Gynecology Hospital of Fudan University

cjw11172@163.com+86 131 6619 1994

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026