Expression and prediction of urinary exosomes in acute kidney injury after radical nephrectomy under different general anesthesia drugs

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400084174

Enrollment

Unknown

Registered

2024-05-11

Start date

2024-05-12

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Radical nephrectomy

Interventions

Desflurane Group:Desflurane anesthesia

Propofol group:Anesthesia with propofol

Eligibility

Sex/Gender

All

Age

40 Years to 80 Years

Inclusion criteria

Inclusion criteria: ? RN patients undergoing elective general anesthesia in our hospital. ? Age 40-80 years old. ? ASA Grade I - III. ? Patients with normal liver and kidney function before operation. ? Obtain informed consent.

Exclusion criteria

Exclusion criteria: ? Patient or the guardian did not sign the informed consent; ? Nephrotoxic drugs were used before surgery. ? History of second kidney operation. ? There was a history of rescue before surgery. ? Major complications occurred during and after operation

Design outcomes

Primary

Measure	Time frame
serum creatinine;	—

Secondary

Measure	Time frame
miRNA-16;miRNA-21;miRNA-200c;	—

Countries

China

Contacts

Public ContactLiu Yong zhe

Third Medical Center, PLA General Hospital

lyzgao@163.com+86 158 1133 1366

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026