Osteoarthropathy of knee joint
Conditions
Interventions
Group Sufentanil:Sufentanil for postoperative analgesia
Group Oxycodone:Oxycodone for postoperative analgesia
Sponsors
Dezhou Hospital, Shandong University Qilu Hospital
Eligibility
Sex/Gender
All
Age
60 Years to 89 Years
Inclusion criteria
Inclusion criteria: 1) Age 60-89 years old; 2) Body Mass Index (BMI) 18-30kg/m2; 3) ASA Level I-III; 4) To prepare for the first unilateral total knee arthroplasty; 5) Participate and cooperate voluntarily and be able to accurately understand or perform oral or physical assessments.
Exclusion criteria
Exclusion criteria: 1) Patients with serious heart, brain, lung, kidney and other organ lesions before surgery; 2) Have a history of knee injury and surgery; 3) Cumulative joint damage, such as rheumatism, RA, systemic lupus erythematosus and other diseases; 4) History of other chronic pain diseases; 5) The skin of the pilot has ruptured or infected; 6) History of opioid use before assessment; 7) long-term use of psychotropic drugs, abuse of alcohol or illicit drugs; 8) Patients with severe mental illness or who have difficulty communicating; 9) Patients who are allergic to narcotic drugs and remedial analgesics; 10) Patients who participated in other clinical trials within the last 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of chronic pain 6 months after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Perioperative and 6 month postoperative VAS scores (resting and exercise);Preoperative and postoperative delirium assessment;Cognitive function assessment;Satisfaction evaluation (VAS=3);nausea and vomiting;Urinary Retentron;Perioperative respiratory and circulatory complications;LOS(length of stay);Field activity time; | — |
Countries
China
Contacts
Public ContactJianbo Wu
The First Affiliated Hospital of Shandong First Medical University
Outcome results
None listed