Peripheral neuropathy caused by chemotherapy
Conditions
Interventions
Intervention group:The ward nurse will assist patients and their family members in donning elastic socks 30 minutes prior to the administration of albumin-bound paclitaxel, and removing them 30 minute
Control group:Routine care
Sponsors
Affiliated Hospital of North Sichuan Medical College
Eligibility
Sex/Gender
Female
Age
26 Years to 69 Years
Inclusion criteria
Inclusion criteria: (1) Female patients diagnosed with breast cancer who are scheduled to undergo a chemotherapy regimen containing albumin-bound paclitaxel (260mg/m2 per dose, administered once every 21 days for a total of 6 cycles); (2) Age: 18 years and older; (3) Possess adequate literacy and cognitive abilities, capable of independently or collaboratively completing questionnaires, and effectively communicating their own needs; (4) Voluntarily participate and provide informed consent.
Exclusion criteria
Exclusion criteria: (1) Patients with a history of exposure to neurotoxic drugs such as vincristine or cisplatin; (2) Those with underlying neurological disorders, diabetes, or other conditions predisposing to peripheral neuropathy and related symptoms; (3) Individuals with localized trauma, infections, lower extremity ulcers, or diabetic foot syndrome; (4) Patients suffering from severe cardiovascular and cerebrovascular conditions; (5) Individuals with known allergies to synthetic materials (e.g. nylon and spandex); (6) Participants in concurrent clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Tactile threshold of the sole; | — |
Secondary
| Measure | Time frame |
|---|---|
| Severity of lower limb peripheral neuropathy;Quality of life;Balance test;Time of first onset of lower limb peripheral neuropathy; | — |
Countries
CHINA
Contacts
Public ContactYuqin Chen
Affiliated Hospital of North Sichuan Medical College
Outcome results
None listed