functional constipation
Conditions
Interventions
Test group:Oral treatment with wheat cellulose granules
Sponsors
Children’s hospital of Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
All
Age
6 Years to 12 Years
Inclusion criteria
Inclusion criteria: 1. Gender unlimited, age 6-12 years old, outpatient 2. It meets the diagnostic criteria of Rome IV functional constipation in children. (Patients with constipation whose main symptoms are reduced frequency of defecation and dry stool are included as far as possible) 3. In the past 1 week, no drugs have been used to affect gastrointestinal motility and treat constipation. Have not used wheat cellulose, compound polyethylene glycol, etc 4. No serious metabolic diseases, no serious cardiovascular, cerebrovascular, lung, liver, kidney and other chronic diseases 5. No clear history of abdominal surgery 6. The patient's family members had good communication skills and were able to complete the records and follow-up according to the requirements of the study protocol. The patient's family members signed informed consent and were willing to participate in the clinical trial
Exclusion criteria
Exclusion criteria: 1. People who are allergic to or have adverse reactions to the same drugs 2. Patients with intestinal obstruction 3. Patients with irritable bowel syndrome 4. There are serious metabolic diseases, serious chronic cardiovascular and cerebrovascular diseases, lung, liver, kidney and other chronic diseases, combined with disease medication may affect gastrointestinal motility and constipation symptoms (such as morphine, spasmolytics, calcium antagonists, etc.) 5. A history of alcohol, poison and/or drug abuse 6. Obvious psycho-psychological disorder Seven. People who have participated in clinical trials of other investigational drugs in the past 12 weeks 8. Constipation due to other diseases, functional defecation disorders and drugs, such as: prorectal swelling, pelvic floor Spasm, megacolon, etc 9. Chronic laxative abusers
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| marked effective rate;effective rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time of onset;Apparent time;Improvement of intestinal flora before treatment and at 28 days; | — |
Countries
Chna
Contacts
Public ContactTing Zhang
Children’s hospital of Shanghai Jiao Tong University School of Medicine
Outcome results
None listed