Genital tract pathogen infection
Conditions
Interventions
Gold Standard:The gold standard for the diagnosis of these five common reproductive tract pathogens is fluorescent quantitative PCR
Index test:PCR combined with microfluidic chip
Sponsors
Huashan Hospital affiliated to Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: (1) Inclusion criteria of positive group: A. Age =18 years old, male or female; B. A history of non-marital sexual intercourse or a history of sexual partner infection; C. Clinically diagnosed gonorrhea, urethritis, vaginitis, etc., and identified any infection of five reproductive tract pathogens (NG, UU, MG, MH, CT) by routine examination method or PCR; D. Fully understand the research content, able to participate in the follow-up research behavior, I am willing to cooperate and participate in the whole process. And cooperate to sign informed consent. For patients without civil capacity, their client needs to agree and sign a consent form, and can cooperate with the full follow-up. (2) Inclusion criteria of control group: A. Age between 18 and 85 years old, male or female; B. Five kinds of reproductive tract pathogens (NG, UU, MG, MH, CT) were excluded by routine examination or PCR; C. Fully understand the research content and can participate in the follow-up research behavior, and I am willing to cooperate and participate in the whole process. And cooperate to sign informed consent.
Exclusion criteria
Exclusion criteria: A. Patients in the medication period, after sexual life or menstruating period at the time of initial sampling; B. Patients with other major systemic diseases (such as myocardial infarction, cerebrovascular disease, epilepsy, malignant tumor, etc.) or mental abnormalities that affect their follow-up and cooperation with the examination; C. Pregnant patients; D. Patients enrolled in other trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sensitivity and specificity of nucleic acid detection of Neisseria gonorrhoeae;Sensitivity and specificity of nucleic acid detection of Ureaplasma urealyticum ;Sensitivity and specificity of nucleic acid detection of Mycoplasma genitalium;Sensitivity and specificity of nucleic acid detection of Mycoplasma hominis;Sensitivity and specificity of nucleic acid detection of Chlamydia trachomatis; | — |
Countries
China
Contacts
Public ContactLu Xiaonian
Huashan Hospital affiliated to Fudan University
Outcome results
None listed