Prostate cancer
Conditions
Interventions
Gold Standard:PSA or traditional imaging was used as the gold standard for the diagnosis of mCRPC and recorded to castration resistance survival time: it refers to the survival time between the diagno
Index test:FDG PET/CT or PSMA PET/CT predicts the time to progression to trend-resistant prostate cancer
Sponsors
Department of urology, The First Affiliated Hospital of Fujian Medical University
Eligibility
Sex/Gender
Male
Age
No minimum to 100 Years
Inclusion criteria
Inclusion criteria: (1) Patients diagnosed with metastatic hormone-sensitive prostate cancer; (2) Undergoing FDG PET/CT and PSMA PET/CT examinations within one month of initiating treatment after the diagnosis of metastatic hormone-sensitive prostate cancer; (3) Generally acceptable physical condition, with an ECOG performance status score of 0-2; (4) Comprehensive clinical, laboratory, and pathological data available.
Exclusion criteria
Exclusion criteria: (1) Presence of other malignancies; (2) Failure to undergo a second round of FDG PET/CT and PSMA PET/CT examinations after entering the castration-resistant prostate cancer stage; (3) History of allergy to the components or similar components of the contrast agents; (4) Severe organ dysfunction, such as severe impairment of heart, lung, liver, or kidney function; (5) Incomplete clinical and pathological data.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| diagnostic sensitivity;diagnostic specificity;positive predictive value;negative predictive value;positive likelihood ratio;negative likelihood ratio;diagnostic accuracy;time to castration-resistant survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| Gross tumor volume;SUVmax, SUVmean, SUVpeak;Overall survival;Biochemical progression free survival; | — |
Countries
China
Contacts
Public ContactNing Xu
The First Affiliated Hospital of Fujian Medical University
Outcome results
None listed