biliary atresia
Conditions
Interventions
Gold Standard:The diagnosis of BA was made by the presence of fibrosing obstruction of extrahepatic biliary remnants excised after intraoperative cholangiography.
Index test:MMP7 rapid test kit showed a postive result.
Sponsors
Union hospital, Tongji medical hospital, Huazhong university of science and technology
Eligibility
Sex/Gender
All
Age
No minimum to 0.5 Years
Inclusion criteria
Inclusion criteria: 1. Signed and dated informed consent form 2. Commit to abide by the research procedures and cooperate with the implementation of the entire research process 3. Infants under 6 months old with symptoms and signs suspected of biliary atresia 4. Be able to persist and cooperate with long-term follow-up visits
Exclusion criteria
Exclusion criteria: Children who are unable to undergo long-term follow-up at the outpatient clinic or online at the medical center where this study was conducted due to their own reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum MMP7; | — |
Secondary
| Measure | Time frame |
|---|---|
| TBIL;DBIL;TBA;Liver Ultrasound;fibrosis and inflammation grade;native liver survival time;Sensitivity;Specificity;Positive predict value;Negative predict value;Accuracy; | — |
Countries
China
Contacts
Public ContactShaotao Tang
Union hospital, Tongji medical hospital, Huazhong university of science and technology
Outcome results
None listed