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Pre IVF/ICSI intake Omega 3 Fatty Acid in PCOS patients:A multicenter, randomized, double-blind, placebo-controlled clinical trial

Pre IVF/ICSI intake Omega 3 Fatty Acid in PCOS patients:A multicenter, randomized, double-blind, placebo-controlled clinical trial

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400084087
Enrollment
Unknown
Registered
2024-05-10
Start date
2025-06-01
Completion date
Unknown
Last updated
2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Polycystic ovary syndrome

Interventions

Experimental group:?- 3 fatty acid ethyl ester 90 soft capsules
Control group:Oral placebo

Sponsors

Lan Zhou University Second Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 37 Years

Inclusion criteria

Inclusion criteria: 1) Meets PCOS diagnostic criteria*; 2) BMI 18-28 kg/m^2; 3) Patients aged 20-37 years old; 4) The patient has indications for IVF/ICSI; 5) Choose antagonist or agonist regimens to promote ovulation. *Using the Rotterdam standard: ? menstrual abnormalities such as infrequent ovulation or anovulation; ? Clinical manifestations of hyperandrogenism and/or hyperandrogenism; ? Polycystic changes in the ovaries. According to the above two criteria, excluding other diseases that cause ovulation disorders (including thyroid dysfunction, premature ovarian failure, hypothalamic pituitary amenorrhea, hyperprolactinemia, etc.), as well as diseases that cause hyperandrogenism (including Cushing syndrome, non classical adrenal reproductive organ syndrome, endocrine tumors that secrete androgens, etc.), the diagnosis can be made.

Exclusion criteria

Exclusion criteria: 1) Used supplements (fish oil, vitamins, etc.) in the past 12 weeks; 2) Sperm collection through testicular or epididymal puncture; 3) PGT cycle; 4) Severe systemic diseases; 5)Severe pathological conditions of the uterus and fallopian tubes.

Design outcomes

Primary

MeasureTime frame
Good quality embryo rate;Clinical pregnancy rate;

Secondary

MeasureTime frame
OHSS incidence rate;Blood lipid levels;insulin resistance ;

Countries

China

Contacts

Public ContactFang Wang

Lan Zhou University Second Hospital

ery_fwang@lzu.edu.cn+86 139 1930 2888

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026