Heart Disease
Conditions
Interventions
Group B (Bupivacaine Liposome Group):A parasternal block combined with a rectus sheath block was performed at the onset of surgery, utilizing bupivacaine liposome at a dosage of 266 mg in a total volu
Group C (Ropivacaine Group):Prior to the commencement of surgery, a parasternal block in conjunction with a rectus sheath block was administered using 0.375% ropivacaine, with a total volume of 40 ml,
Sponsors
The First Affiliated Hospital of Guangxi Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: A.Elective Midline Sternotomy Cardiac Surgery Patients. B.American Society of Anesthesiologists (ASA) Physical Status Classification I-III. C.Age Range 18-65 Years,Gender Inclusive. D.Signed Informed Consent.
Exclusion criteria
Exclusion criteria: A.Patients with severe comorbidities affecting heart, lung, liver, or kidney function. B.Individuals with severe neuropsychiatric disorders. C.Candidates with thoracic deformities that prevent neural blockade. D.Those with a history of two or more open-chest surgeries. E.Participants with a BMI greater than or equal to 28. F.Individuals with alcohol or opioid addiction. G.Subjects with hyperalgesia. H.Patients allergic to local anesthetics. I.Volunteers unwilling to accept experimental procedures.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative analgesic dosage;Visual Analogue Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Occurrence of Chronic Post-Surgical Pain (CPSP) at 3 and 6 months postoperatively.; | — |
Countries
China
Contacts
Public ContactYizhi Lu
The First Affiliated Hospital of Guangxi Medical University
Outcome results
None listed