Postpartum depression
Conditions
Sponsors
Department of Anesthesiology, Xiangya Third Hospital, Central South University
Eligibility
Sex/Gender
All
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1) Spinal anesthesia/combined spinal epidural anesthesia for cesarean section women; 2) = 18 years old; 3) Meets the American Society of Anesthesiologists (ASA) physical condition classification II-III risk assessment criteria; 4) The patient fully understands the purpose and requirements of the trial, is able to communicate well with the follow-up, agrees to participate in this trial, and voluntarily signs an informed consent form.
Exclusion criteria
Exclusion criteria: 1) Unable to understand the language ability of the follow-up patient and communicate effectively; 2) Having unstable mental or depressive disorders; 3) Have a history of abuse of psychotropic drugs and alcohol; 4) Long term use of antidepressants within the first 6 months of the study; 5) Participate in other clinical drug trials; 6) Taboos for spinal anesthesia/combined spinal epidural anesthesia, requiring general anesthesia or natural delivery; 7) During the study, antidepressants were used through any route of administration; 8) The researchers believe that mothers with any other factors that may affect the trial results, increase maternal risk, etc. are not suitable to participate in this clinical study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| kynurenine;Quinolinic acid;kynurenic acid;Quinolinic acid phosphoribosyltransferase; | — |
Secondary
| Measure | Time frame |
|---|---|
| Tryptophan;3-Hydroxy-kynurenine;Pyridinic acid; | — |
Countries
Chian
Contacts
Public ContactWang Saiying,Duan Kaiming
Department of Anesthesiology, Xiangya Third Hospital, Central South University
Outcome results
None listed