Obstructive sleep apnea
Conditions
Interventions
Experimental group:Six hours after the patient returned to the ward, pregabalin 300 mg/day (150 mg twice a day) was taken orally until discharge
control group:nothing
Sponsors
Department of Anesthesiology, Qilu Hospital, Shandong University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) Age 18-70 years old, gender is not limited (2) OSA patients undergoing elective UPPP (3) American Society of Anesthesiologists (ASA) grade I-III (4) Voluntarily participate in the study and sign the informed consent form
Exclusion criteria
Exclusion criteria: (1) Those with a history of severe heart, lung and other systemic diseases (2) Patients with a history of psychiatric illness or preoperative cognitive dysfunction who are unable to cooperate with the evaluation (3) Those who have a history of allergy to intraoperative drugs (4) Patients with severe liver, kidney and blood system dysfunction
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The patient's 24h postoperative pain numerical analogue scale (NRS) score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Troponin (CTnI) value 48h after surgery;NRS score 12h 36h 48h after surgery;The number and dosage of postoperative analgesic drugs;Total perioperative opioid use;Basic vital signs during surgery (blood pressure, heart rate, pulse, oxygen saturation, etc.);The patient's postoperative extubation time;Incidence of chronic pain at 3 months postoperatively in patients; | — |
Countries
China
Contacts
Public ContactShuhai Tang
Qilu Hospital, Lixia District, Jinan City, Shandong Province
Outcome results
None listed