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A prospective randomized clinical study comparing the effect of bilateral R3 thoracic sympathectomy in the treatment of multisite moderate to severe primary hand hyperhidrosis

A prospective randomized clinical study comparing the effect of bilateral R3 thoracic sympathectomy in the treatment of multisite moderate to severe primary hand hyperhidrosis

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400084069
Enrollment
Unknown
Registered
2024-05-09
Start date
2024-05-13
Completion date
Unknown
Last updated
2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Surgical treatment of Primary palmar hyperhidrosis

Interventions

Experimental group:Unilateral R3 thoracic sympathectomy
Control group:Bilateral R3 thoracic sympathectomy

Sponsors

The Third People's Hospital Of Shenzhen
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 65 Years

Inclusion criteria

Inclusion criteria: (1) Patients with multiple sites of moderate to severe primary hyperhidrosis who are willing to undergo surgery, specifically manifested as patients with hand hyperhidrosis accompanied by sweating on the feet, underarms or face. (2) Age 15-65 years old. (3) Patients who understand and accept postoperative compensatory sweating and recurrence of postoperative hand sweating.

Exclusion criteria

Exclusion criteria: (1) Patients with recent tuberculosis, malignant tumor, hyperthyroidism and other endocrine diseases or hypothalamic central diseases. (2) Patients with autoimmune vasculitis, thoracic outlet syndrome, empyema and tuberculosis in the past caused dense adhesions of the pleura. (3) Serious bradycardia with electrocardiogram heart rate New York Heart Association (NYHA) class II. Lung function: FEV1<1.5L, MVV<50% of predicted value. (7) Those who have poor compliance and cannot complete the planned follow-up. 8. Patients considered by the investigator to be unsuitable for participating in this trial.

Design outcomes

Primary

MeasureTime frame
Hyperhidrosis relief degree;

Secondary

MeasureTime frame
Treatment effect evaluation;Patient satisfaction;

Countries

China

Contacts

Public ContactShi Qinlang

The Third People's Hospital Of Shenzhen

shiqinlang@live.cn+86 137 1225 8808

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026