bladder inflammatory diseases
Conditions
Interventions
the group of intravesical PRP treatment:PRP injection or instillation
Sponsors
The urology department of Beijing Chaoyang Hospital affiliated to Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1.Patients aged 18 to 75 years old, regardless of gender 2.Patients with symptoms of frequent urination, urgency, painful urination, or bladder pain 3.After routine treatment (behavioral therapy, oral medication, bladder infusion, etc.), the effect is poor (GRA score = 4 after treatment) 4.The patient or its legal representative has signed a written informed consent form
Exclusion criteria
Exclusion criteria: 1 Patients with hunner's lesions confirmed by cystoscopy 2. Uncontrolled acute urinary tract infection 3. Bladder outlet obstruction and urethral stricture caused by various reasons 4. Patients with a residual urine volume of> 250ml 5. Neurogenic bladder 6. Benign and malignant tumors 7. Patients with contraindications to catheterization during treatment 8. Uterine, cervical, vaginal or urethral cancer 9. Infectious diseases of the urinary and reproductive systems 10. Contraindications to catheterization during treatment 11. Abnormal decrease in platelets and other abnormalities in the blood system 12. Patients with abnormal laboratory test results during screening, including ALT>3 x upper limit of normal range, AST>3 x upper limit of normal range, and abnormal serum creatinine levels>2 x upper limit of normal range 13. Pregnant, lactating, and pre pregnancy women 14. Suffering from severe cardiovascular and pulmonary diseases, such as congestive heart failure, uncontrolled hypertension, etc., unable to receive regular follow-up 15. Patients with any other serious illness that the researcher deems unsuitable to participate in the trial
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| General reaction assessment; | — |
Secondary
| Measure | Time frame |
|---|---|
| Urinary diary;Urodynamic test;O'leary-sant score;Pain visual analogue scale score,VAS;Quality of Life score,QOL;Pelvic pain and urgency,frequency score,PUF; | — |
Countries
China
Contacts
Public ContactZhang Peng
Beijing Chaoyang Hospital affiliated to Capital Medical University
Outcome results
None listed