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Application Research of FDG PET/CT and PSMA PET/CT in the Assessment of Therapeutic Efficacy for Castration-Resistant Prostate Cancer

Application Research of FDG PET/CT and PSMA PET/CT in the Assessment of Therapeutic Efficacy for Castration-Resistant Prostate Cancer

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400084064
Enrollment
Unknown
Registered
2024-05-09
Start date
2024-05-15
Completion date
Unknown
Last updated
2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prostate cancer

Interventions

Case series:One FDG PET/CT and PSMA PET/CT examination should be conducted within the month prior to the initiation of treatment for castration-resistant prostate cancer (CRPC) and upon the occurrence

Sponsors

Department of urology, The First Affiliated Hospital of Fujian Medical University
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
No minimum to 100 Years

Inclusion criteria

Inclusion criteria: (1) Patients diagnosed with castration-resistant prostate cancer (CRPC) according to the PCWG3 diagnostic criteria; (2) PSMA PET/CT and FDG PET/CT examinations conducted within the month prior to the initiation of CRPC treatment; (3) ECOG performance status score of 0-2; (4) Comprehensive clinical and pathological data available.

Exclusion criteria

Exclusion criteria: (1) Presence of other malignancies; (2) Failure to undergo a second round of PSMA PET/CT and FDG PET/CT examinations upon occurrence of PSA progression or conventional radiological progression after initiation of CRPC treatment; (3) History of allergy to the components or similar components of the contrast agents; (4) Severe organ dysfunction, such as severe impairment of heart, lung, liver, or kidney function; (5) Incomplete clinical and pathological data.

Design outcomes

Primary

MeasureTime frame
Overall Survival;Radiographic Progression Free Survival;Objective Response Rate;Disease Control Rate;

Secondary

MeasureTime frame
Time to first subsequent therapy;

Countries

China

Contacts

Public ContactNing Xu

The first affiliated hospital of Fujian Medical Univeraity

drxun@fjmu.edu.cn+86 132 3590 7575

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026