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Effect of SGLT2 inhibitors on cardiac autonomic function and prognosis in patients with acute myocardial infarction

Effect of SGLT2 inhibitors on cardiac autonomic function and prognosis in patients with acute myocardial infarction

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400084050
Enrollment
Unknown
Registered
2024-05-09
Start date
2024-05-09
Completion date
Unknown
Last updated
2024-09-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acute myocardial infarction

Interventions

DAPA group:Dagliflozin 10mg per day was added to the standard treatment
DAPA-free group:standard treatment

Sponsors

The Second Affiliated Hospital of Anhui Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. Age 18-90 years; 2. All were diagnosed with ST-segment elevation myocardial infarction or non-ST-segment elevation myocardial infarction according to the guidelines; 3.

Exclusion criteria

Exclusion criteria: 1. pregnant or lactating women; 2. eGFR <45 mL/min/1.73 m2; 3. type 1 diabetes mellitus; 4. acute urinary tract infection or genital infection; 5. has a pacemaker; 6. persistent atrial fibrillation; 7. has not signed an informed consent form; 8. is currently on treatment with any SGLT-2 inhibitors; 9. Known allergy to SGLT-2 inhibitors

Design outcomes

Primary

MeasureTime frame
Cardiac autonomic function;

Secondary

MeasureTime frame
left ventricular remodeling index;Incidence of adverse cardiovascular events;

Countries

China

Contacts

Public ContactJun Wan

The Second Affiliated Hospital of Anhui Medical University

ayd2fyemergency@163.com+86 147 0551 1559

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026