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Comparison of Ciprofol and Propofol in Painless Induced Abortion

Comparison of Ciprofol and Propofol in Painless Induced Abortion

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400084024
Enrollment
Unknown
Registered
2024-05-09
Start date
2024-01-02
Completion date
Unknown
Last updated
2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Painless Induced Abortion

Interventions

Ciprofol group:1.Respiratory arrest occurs when spontaneous breathing stops for more than 20 seconds. Immediately apply pressurized mask oxygen supply. 2. Hypotension: the mean arterial pressure is 30
propofol group:1.Respiratory arrest occurs when spontaneous breathing stops for more than 20 seconds. Immediately apply pressurized mask oxygen supply. 2. Hypotension: the mean arterial pressure is 30

Sponsors

The First Affiliated Hospital of Yangtze University,Jingzhou,Hubei,China
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: (1) Age 18 to 50 years old, ASA grade: I - II, no airway block, BMI: 18 ~ 30kg/?; (2) Intrauterine early pregnancy and painless induced abortion; (3) The clinical data are complete and accurate; (4) No obvious dysfunction of heart, lung, liver, kidney and other important organs; (5) Patients and their families fully understand the process of this study, are willing to sign the informed consent form and comply with the order strictly as required.

Exclusion criteria

Exclusion criteria: (1) Those who refuse to participate or are not suitable to participate in this trial; (2) Those who have been allergic to eggs, beans, opioids and propofol; (3) Patients with severe organ function disorders, ASA grade III or above; (4) Patients with paroxysmal sleep apnea syndrome and asthma; (5) People with mental, language and behavioral dysfunction; (6) Recent use of sedatives or opioids.

Design outcomes

Primary

MeasureTime frame
injection pain;Body movement;Respiratory inhibition;Hypoxemia;Nausea and vomiting;blood Pressure;blood Pressure;blood Pressure;blood Pressure;blood Pressure;heartrate;heartrate;heartrate;heartrate;heartrate;Pulse oxygen saturation;Pulse oxygen saturation;Pulse oxygen saturation;Pulse oxygen saturation;Pulse oxygen saturation;Respiratory rate;Respiratory rate;Respiratory rate;Respiratory rate;Respiratory rate;MOAA/S score;MOAA/S score;MOAA/S score;MOAA/S score;MOAA/S score;dizzy;Narcotrend Index ;Narcotrend Index ;Narcotrend Index ;Narcotrend Index;Narcotrend Index;

Secondary

MeasureTime frame
onset time;operation time;recovery time;orientation recovery time;retention time in the anesthesia recovery room;otal amount of intravenous anesthetic;VAS (visual analogue scale) pain score;the satisfaction of patients with anesthesia;the satisfaction of surgeons with anesthesia;

Countries

China

Contacts

Public ContactRui Xia

The First Affiliated Hospital of Yangtze University,Jingzhou,Hubei,China

879560350@qq.com+86 189 7216 1338

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026