General anesthesia induction
Conditions
Interventions
0.25mg/kg Remimazolam Tosilate group:Intravenous injection of different doses of Remimazolam Tosilate
Remimazolam 0.30mg/kg:Remimazolam 0.30mg/kg,
Remimazolam 0.35mg/kg Group:Remimazolam 0.35mg/kg
Remimazolam 0.40mg/kg Group:Remimazolam 0.40mg/kg
Sponsors
Jiaxing Maternity and Child Health Care Hospital
Eligibility
Sex/Gender
Female
Age
65 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) Age =65 years old; 2) The American Association of Anesthesiologists (ASA) has a physical status rating of II-III; 3) 18 kg/m2<BMI<30 kg/m2 ; 4) hysteroscopic general anesthesia; 5) Understand clearly and voluntarily participate in the study, and sign the informed consent form by myself or my family.
Exclusion criteria
Exclusion criteria: 1) Patients who are allergic to benzodiazepines; 2) Patients with myasthenia gravis; 3) patients with schizophrenia; 4) Patients with severe depression; 5) Hypertension is not controlled (preoperative systolic blood pressure =160mmHg) and diabetes is not controlled (=11.1mmol/L).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intubation stress reaction (jaw relaxation, no body movement);Hemodynamic changes; | — |
Secondary
| Measure | Time frame |
|---|---|
| blood pressureHR;SPO2;Anesthetic effects;Psychomotor recovery; | — |
Countries
China
Contacts
Public ContactQiang Xu;Wang Ping Zhang
Jiaxing Maternal and Child Health Care Hospital
Outcome results
None listed