Modeling of breast cancer organoids based on microfluidic system and its drug susceptibility analysis

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2400083986

Enrollment

Unknown

Registered

2024-05-08

Start date

2023-05-20

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast cancer

Interventions

Negative control group:Traditional embedding method to culture organoids

Experimental group:Microfluidic culture of organoids

Eligibility

Sex/Gender

Female

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Breast cancer patients; 2. TNM staging: T2-T3, N1 and above, M0; 3. The tumor has a diameter greater than two centimeters and has not invaded the chest wall or skin; Has spread to the axillary lymph nodes; No distant organ metastasis occurred.

Exclusion criteria

Exclusion criteria: Patients had a history of previous treatment.

Design outcomes

Primary

Measure	Time frame
Organizational characteristics, biomarkers, and expression of resistance genes;Drug sensitivity analysis results;	—

Secondary

Measure	Time frame
Average diameter and proliferation ability;	—

Countries

China

Contacts

Public ContactYang Jun

Shanxi Provincial Cancer Hospital

745856514@qq.com+86 138 3422 7616

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026