A comparative study of 18F-FDG PET/CT myocardial metabolism imaging under fasting and G/I loading

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2400083975

Enrollment

Unknown

Registered

2024-05-08

Start date

2022-08-05

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

18F-FDG PET/CT myocardial metabolism imaging under G/I loading

Interventions

Gold Standard:18F-FDG PET/CT myocardial metabolism imaging under G/I loading

Index test:Qualitative analysis indicators (5-point scoring system, positive or not on perfusion-metabolism mismatch extent polar map) Quantitative analysis indicators (basic information of subjects:

History: hypertension, hyperlipidemia, DM, CABG/PTCA, myocardial infarction (MI), smoking, recent ECD LVEF. Left ventricular cardiovascular pool SUVmean (B), left ventricular myocardial SUVmax (M), M/

Data in the examination process: FBG, pre-injection BG, pre-imaging BG, peak BG, insulin dosage, G/I load time (from oral glucose to injection developer, MPP)

perfusion-metabolism mismatch extent polar map map percentage of total, LAD, LCX or RCA, PET LVEF, left ventricular dyssynchrony)

Eligibility

Sex/Gender

All

Age

18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1) Age 18 to 85 years old, no gender restrictions; 2) Coronary heart disease suspected myocardial ischemia; 3) Can persist in completing 99mTc-MIBI myocardial blood perfusion imaging and 18F-FDG PET/CT myocardial metabolism imaging.

Exclusion criteria

Exclusion criteria: 1) Pregnant or lactating patients; 2) Combined with tumor; 3) Combined with other clear infection history; 4) There are contraindications of nuclear medicine imaging mentioned above.

Design outcomes

Primary

Measure	Time frame
SUVmean of blood pool;SUVmax of the myocardium;M/B ratio;positive or not on perfusion-metabolism mismatch extent polar map;perfusion-metabolism mismatch extent polar map map percentage of total, LAD, LCX or RCA;PET LVEF;left ventricular dyssynchrony;Accuracy ;	—

Secondary

Measure	Time frame
sensitivity;specificity;Positive predictive value;Negative predictive value;Blood glucose;	—

Countries

China

Contacts

Public ContactShi Hongcheng

Zhongshan Hospital, Fudan University

shi.hongcheng@zs-hospital.sh.cn+86 136 8197 1579

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 20, 2026