Bone and joint disease
Conditions
Interventions
Group of the fluid gelatin:use fluid gelatin on surgical site
Group of tranexamic acid:use 1g tranexamic acid on surgical site
Sponsors
West China Hospital of Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: (1) Patients with unilateral primary total knee arthroplasty; (2) ASA classification: 1-II1; (3) Age 18-80 years old
Exclusion criteria
Exclusion criteria: (1) Allergic to fluid gelatin; (2) Bleeding diseases and coagulation dysfunction (including various blood diseases and liver diseases, such as thrombocytopenia to <50x10?, severe liver disease caused by hepatitis B, hepatitis C and other severe liver diseases accompanied by coagulation dysfunction, etc.) are not controlled: (3) Anticoagulant drugs are currently being used, such as warfarin; (3) The orthopedic surgeon judged that there were contraindications to surgery: (4) Refusal to participate in the clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hb; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hematocrit;Amount of blood loss during surgery;Degree of swelling;blood Drainage;score of pain;Postoperative complications;Joint range of motion; | — |
Countries
China
Contacts
Public ContactZongke Zhou
West China Hospital of Sichuan University
Outcome results
None listed