keloid
Conditions
Interventions
Test group:Oral Sanjie Quehua formula (preparation of Sino-Japanese Friendship Hospital, the ingredients are three rhizome, Zedoary, Astragalus, Prunella, Thunberg Fritillaria, raw oyster, saponaria s
Control group:Without intervention.
Sponsors
Department of Dermatology, China-Japan Friendship Hospital
Eligibility
Sex/Gender
All
Age
1 Years to 80 Years
Inclusion criteria
Inclusion criteria: ? Diagnostic criteria for keloid: The case collection is mainly based on outpatients from the dermatology department of China-Japan Friendship Hospital, and the included cases must meet the clinical diagnostic criteria for keloid. The diagnostic criteria refer to the criteria proposed by Cai Jinglong et al.: the lump protrudes from the surface of the skin, is hard, smooth and shiny, has irregular boundaries, and shows no signs of regression within one year; The lesion extends beyond the original edge of the injury and infiltrates the surrounding normal tissue, forming a crab foot like growth pattern; Has clinical symptoms such as persistent growth, redness, pain, and itching, without a tendency to self heal and cannot resolve on its own; Simple surgical resection is prone to recurrence, and the recurrence range can exceed the original scar range; Pathological examination confirmed a significant deposition of collagen and matrix components in scar tissue, with numerous fibroblasts and a mitotic phase [8]. ? Traditional Chinese medicine differentiation criteria for keloids: combining skin lesion differentiation with overall differentiation, the scar color is dark red, with local pain and refusal to press, and the pain is more severe than itching. Accompanied by forgetfulness, hypochondriac pain, and distension, women may have dysmenorrhea, tongue ecchymosis, and fine and astringent pulse, which belongs to the syndrome of qi stagnation and blood stasis. ? Meets the diagnostic criteria for keloids, and the differentiation of skin lesions belongs to the syndrome of qi stagnation and blood stasis. ? After one month, there was no wound or the wound healed well and completely epithelialized at the scar site. ? The subjects voluntarily joined the study and signed an informed consent form.
Exclusion criteria
Exclusion criteria: ? Scars that do not conform to the differentiation of qi stagnation and blood stasis syndrome. ? There are other serious liver, kidney, heart, and hematopoietic system diseases. ? Unable to cooperate with the experiment if there are obvious mental symptoms. ? Pregnant women or other researchers are aware that it is not suitable to participate in the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| efficient; | — |
Secondary
| Measure | Time frame |
|---|---|
| hypertrophic index, HI;Patient satisfaction evaluation; | — |
Countries
China
Contacts
Public ContactLiu Qingwu
Department of Dermatology, China-Japan Friendship Hospital
Outcome results
None listed