Painless Ovulation retrieval
Conditions
Interventions
test group 1:Targeted control infusion of 0 ng/ml alfentanil
test group 2:Targeted control infusion of 15ng/ml alfentanil
test group 3:Targeted control infusion of 30 ng/ml alfentanil
test group 4:Targeted control infusion of 45 ng/ml alfentanil
test group 5:Targeted control infusion of 60 ng/ml alfentanil
test group 6:Targeted control infusion of 75 ng/ml alfentanil
test group 7:Targeted control infusion of 90 ng/ml alfentanil
test group 8:Targeted control infusion of 105 ng/ml alfentanil
Sponsors
Shanxi Bethune Hospital
Eligibility
Sex/Gender
Female
Age
20 Years to 50 Years
Inclusion criteria
Inclusion criteria: ?Those who intend to undergo painless egg retrieval in our hospital on an elective basis; ? 18.5 kg/? = BMI <28 kg/? ; ? American Society of Anesthesiologists of New York (ASA) grade ? ~ ?, without contraindications to general anesthesia.
Exclusion criteria
Exclusion criteria: ? Those who refuse to sign the informed consent form or are otherwise considered unsuitable for the clinical trial by the investigator; ? Those who have participated in clinical trials of other drugs in the last 4 weeks; ? Those with allergic constitution and allergic asthma; ? Those with a history of alcohol abuse and psychiatric system diseases, or a history of long-term use of psychotropic drugs, or cognitive dysfunction; ? Those with respiratory sleep apnea syndrome or anticipated difficult airway; (vi) Those with a recent history of acute infection; (vii) Those with hearing impairment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Plasma concentrations of afentanil and propofol in each patient at the time of sedation and analgesia; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemodynamic stability;Effects on respiration;Follicle quality;nausea and vomiting;Total consumption of propofol ;Total consumption of alfentanil;Surgery time;awakening time;Immediate post awakening pain score; | — |
Countries
China
Contacts
Public ContactPing Zhuang
Shanxi Bethune Hospital
Outcome results
None listed