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Analysis of the Effect and Prognosis of Different Treatment Regimens on Children with Henoch-Schonlein Purpura Nephritis

Analysis of the Effect and Prognosis of Different Treatment Regimens on Children with Henoch-Schonlein Purpura Nephritis

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400083908
Enrollment
Unknown
Registered
2024-05-07
Start date
2024-05-08
Completion date
Unknown
Last updated
2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Henoch-Schonlein Purpura Nephritis

Interventions

Case group:None

Sponsors

Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 18 Years

Inclusion criteria

Inclusion criteria: (1) Aged between 0 and 18 years old; (2) Met the HSPN diagnostic criteria established by the Nephrology Group of the Pediatrics Branch of the Chinese Medical Association in 2009; (3) Complied with the Classification Criteria II to VI of the Evidence-Based Guide for Diagnosis and Treatment of HSPN issued by the Nephrology Group of the Pediatrics Branch of the Chinese Medical Association in 2016.

Exclusion criteria

Exclusion criteria: (1) Those who did not undergo renal biopsy; (2) Those with incomplete clinical data; (3) Those with severe dysfunction of organs such as the heart, liver, kidneys, and lungs; (4) Those with primary kidney disease or other types of secondary kidney disease; (5) Those who are allergic or intolerant to TAC, MMF, CTX, or steroids.

Design outcomes

Secondary

MeasureTime frame
24-hour urine protein;Urine albumin creatinine ratio;Urine routine;

Primary

MeasureTime frame
Induction treatment outcomes in terms of renal remission at 1, 3, 6, and 12 months after treatment;Blood albumin;Serum creatinine;Immunoglobulin;2,25-(OH)? vitamin D?;Total serum IgE level;

Countries

China

Contacts

Public ContactZhou Jianhua

Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology

jhzhou@tjh.tjmu.tdu.cn+86 133 6726 6559

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026