Henoch-Schonlein Purpura Nephritis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Aged between 0 and 18 years old; (2) Met the HSPN diagnostic criteria established by the Nephrology Group of the Pediatrics Branch of the Chinese Medical Association in 2009; (3) Complied with the Classification Criteria II to VI of the Evidence-Based Guide for Diagnosis and Treatment of HSPN issued by the Nephrology Group of the Pediatrics Branch of the Chinese Medical Association in 2016.
Exclusion criteria
Exclusion criteria: (1) Those who did not undergo renal biopsy; (2) Those with incomplete clinical data; (3) Those with severe dysfunction of organs such as the heart, liver, kidneys, and lungs; (4) Those with primary kidney disease or other types of secondary kidney disease; (5) Those who are allergic or intolerant to TAC, MMF, CTX, or steroids.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| 24-hour urine protein;Urine albumin creatinine ratio;Urine routine; | — |
Primary
| Measure | Time frame |
|---|---|
| Induction treatment outcomes in terms of renal remission at 1, 3, 6, and 12 months after treatment;Blood albumin;Serum creatinine;Immunoglobulin;2,25-(OH)? vitamin D?;Total serum IgE level; | — |
Countries
China
Contacts
Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology