Lung cancer
Conditions
Interventions
Gold Standard:Pathological results of biopsy or surgery
Index test:Combined methylation and metabolomics detection
Sponsors
Zhongshan hospital, Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: a)CT findings in patients with pulmonary nodules (6-30 mm), patients requiring pathological diagnosis, or normal people with no abnormalities in the lung CT examination . b) Sign informed consent c) Age 18-80
Exclusion criteria
Exclusion criteria: a) Previous history of malignant tumor b) Unwillingness to sign informed consent c) Pregnant persons
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The performance of blood methylation detection, the performance of metabolomics detection, the performance of blood methylation index combined with metabolomics multi-omics detection for the identification of benign and malignant pulmonary nodules, and combined with LDCT and other imaging techniques to improve the accuracy of benign and malignant pulmonary nodules; | — |
Secondary
| Measure | Time frame |
|---|---|
| Screening of metabolite targets and methylation targets in Chinese lung cancer population; Relationship between metabolite targets and methylation targets and pathological classification and staging of lung cancer; | — |
Countries
China
Contacts
Public ContactYong Zhang
Zhongshan hospital, Fudan University
Outcome results
None listed