Skip to content

Oxalidine and sufentanil for patient-controlled analgesia after video-assisted thoracoscopic surgery: a single-center, prospective, randomized, controlled, double-blind case-control study

Oxalidine and sufentanil for postoperative analgesia after video-assisted thoracoscopic surgery: a single-center, prospective, randomized, controlled, double-blind case-control study

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400083856
Enrollment
Unknown
Registered
2024-05-06
Start date
2024-05-06
Completion date
Unknown
Last updated
2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute pain after thoracoscopic surgery

Interventions

Group A: Oseley set group:Oxalidine 30mg + 70ml saline 100ml, the first dose 1.5mg (5ml), PCA 0.35mg (1.2ml), interval 6min, no background measurement, the maximum dose was 70ml/ days.
Group B: Sufentanil group:sufentanil 100ug + 100ml saline 100ml, first dose 5ug (5ml), PCA 1.2ug (1.2ml), interval 6min.

Sponsors

Shanghai Fourth People's Hospital affiliated to Tongji University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. The age ranges from 18 to 75 years old, regardless of sex. 2. Thoracoscopic surgery is planned. Patients who need patient-controlled intravenous analgesia after operation. 3. ASA I-III level; 4. Voluntarily participate and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Chronic pain, long-term use of analgesics, psychiatric drugs (including opioids, NSAIDs, sedation, antidepressants), alcohol abuse; 2. Allergic to research drugs; 3. BMI& gt;40kg/m2 or BMI<20kg/m2; 4. Patients who are unable to cooperate with shock and mental disorders; 5. Have severe heart or liver disease; 6. Acute and chronic bronchial asthma; 7. Suspected gastrointestinal obstruction; 8. A pregnant woman or pregnant woman. 9. Sleep apnea; 10. Participated in other drug trials in three months.

Design outcomes

Primary

MeasureTime frame
Pain intensity within 24 hours after operation (using visual analogue scale, VAS);

Secondary

MeasureTime frame
Total consumption of analgesics;Incidence of side effects (e.g. nausea, vomiting, respiratory depression: respiratory rate & lt;8 / min or finger pulse oxygen saturation<90%);Hospitalization time;Patient satisfaction;Postoperative ICU stay time;

Countries

CHINA

Contacts

Public ContactTan Jingjing

Department of Anesthesia and Perioperative Medicine

86919424@qq.com+86 132 9912 5785

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026