anal fissure
Conditions
Interventions
Control Group:Nitroglycerin Ointment is applied to the wound once in the morning and once in the evening for a period of 14 days.
Experimental Group:Kuiyangyu Ointment is applied to the wound once in the morning and once in the evening for a period of 14 days.
Sponsors
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) Patients who meet the western medical diagnostic criteria for Stage I and II anal fissure and the Chinese medicine diagnosis of blood-heat and intestinal dryness; (2) Age =18 and =65 years old, gender is not limited; (3) Have not used other topical drugs for anal fissure in the past 1 week; (4) Understand and agree to participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Pregnant or breastfeeding women, allergic individuals and those who are allergic to the drugs involved in this study; (2) Previous history of anal and intestinal diseases and other surgeries, or significant abnormal anal function; (3) Patients with a combination of other perianal diseases, such as mixed hemorrhoids, perianal abscess, anal fistula, colorectal tumours and so on; (4) Patients with inflammatory bowel disease, such as ulcerative colorectitis and Crohn's disease; (5) Combined with cardiovascular, cerebrovascular, hepatic, renal and hematopoietic systems and other serious primary diseases and psychiatric patients; (6) Patients with delayed wound healing due to infection with tuberculosis, diabetes mellitus, and various consumptive diseases and seeing moderate to severe malnutrition; (7) Participated in or are participating in other clinical trials in the month before enrolment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total Effective Rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain scores;Degree of blood in stool;Scoring of granulation tissue growth;Wound healing time;Incidence of adverse reactions; | — |
Countries
China
Contacts
Public ContactLi Ying
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine
Outcome results
None listed