Skin aging
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) From 25 to 55 years old, Asian (China), healthy female or male; (2) The residence is the location of the testing institution; (3) Sensitive muscle classification questionnaire was assessed as sensitive muscle and had a positive lactic acid tingling test (3 points); (4) The face has a certain degree of eye lines (level 3 and above), crow's feet (level 3 and above), head lines (level 2 and above), Sichuan lines (level 1 and above), mouth lines (level 1 and above), law lines (level 2 and above), (wrinkle classification refer to the skin aging map (Volume 2 Asian)); (5) Facial skin relaxation; (6) Able to understand the test process, volunteer to participate in the test and sign the written informed consent.
Exclusion criteria
Exclusion criteria: (1) The application of any topical drug at the test site within the last two months; (2) Using antihistamines in the past week or immunosuppressants in the last month; (3) Patients with inflammatory skin disease; (4) Patients with insulin-dependent diabetes mellitus; (5)Patients with asthma or other chronic respiratory diseases under treatment; (6) Those who have received anti-cancer chemotherapy in the past six months; (7) Patients with immunodeficiency or autoimmune diseases; (8) Women born during pregnancy or lactation; (9) Significant scar, pigmentation, atrophy, bright red nevus, sunburn, wounds, wear, in or near the skin test site Tattoo or other defects that may affect the determination of the test results; (10) In the past three months, those who have received photorejuvenation, laser and other medical and aesthetic treatments or other facial beautification methods that may affect the skin condition; (11) Participated in similar facial tests, oral drug trials or other clinical trials in the past 2 months; (12) Highly sensitive physique, known allergic to cosmetics or daily chemical ingredients, alcohol, rubber or drugs; (13) Those who need to be exposed to outdoor daylight for a long time due to work or other reasons; (14) Other iatrogenic problems may affect the test results (such as coagulopathy, severe hyperglycemia, high Blood pressure, hyperlipidemia, mental illness or other major diseases); (15) Non-volunteer participants or those who cannot complete the prescribed trial content as required.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Self-assessment of subject;Facial image uptake and analysis;Image analysis of facial wrinkles;The measurement of skin elasticity ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Lactic acid stinging test;The measurement of skin firmness; | — |
Countries
China
Contacts
Dermatology Hospital of Southern Medical University