gallstone
Conditions
Interventions
Control group :The same amount of normal saline was given during the operation.
intervention group:Intraoperative continuous infusion of esketamine (0.5mg/kg/h)
Sponsors
People's Hospital of Ningxia Hui Autonomous Region
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1) Patients =18 years of age who are undergoing laparoscopic gallbladder surgery. 2) American Society of Anesthesiologists Physical Status ?-?. 3) BMI 18-30 kg/m2.
Exclusion criteria
Exclusion criteria: 1) Patients with contraindications associated with esketamine. 2) Patients with pre-existing schizophrenia, epilepsy, Parkinson's disease, or myasthenia gravis. 3) Patients with severe dementia, speech impairment, coma, etc., who are unable to complete the preoperative assessment. 4) Patients with preoperative sleep disturbance (Pittsburg Sleep quality score =7). 5) Patients currently using sleeping pills or antidepressants. 6) Body mass index (BMI) > 30 kg/m 2. 7) Patient refusal to participate in the study.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| VAS;HADS;The dosage and frequency of postoperative remedial analgesia;Postoperative adverse reactions; | — |
Primary
| Measure | Time frame |
|---|---|
| Postoperative sleep disturbance; | — |
Countries
China
Contacts
Public ContactYe Zhenhai
People's Hospital of Ningxia Hui Autonomous Region
Outcome results
None listed