600# Tian He Road, Guangzhou, P.R. China
Conditions
Interventions
Gold Standard:ultrasound-guided fine needle aspiration of lymph node
Index test:high frame-rate contrast-enhanced ultrasonography
Sponsors
the Third Affiliated Hospital of Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1) PTC Patients 2) indeterminate cervical lymph nodes determined by high frequency ultrasonography, and meets all the following: a. absence of a hilum; b. one of the following characteristics appears: round shape, increased short axis (=8mm in level II and =5mm levels III and IV), increased central vascularization; c. without microcalcifications, partially cystic appearance, peripheral or diffusely increased vascularization, or hyperechoic tissue looking like thyroid; 3) without history of chemotherapy or radiation therapy for cervical lymph node 4) = 18 years old 5) able to comply with the requirements of the experiment and cooperate with subsequent puncture biopsy (within 3 months after contrast-enhanced ultrasonography) 6) signing informed consent form
Exclusion criteria
Exclusion criteria: 1) allergic of ultrasound contrast agent 2) severe cardiopulmonary dysfunction 3) Pregnant or lactating period 4) with a history of mental illness, personality disorders, cognitive impairment or brain organic diseases, unable to cooperate with contrast-enhanced ultrasonography or pathological examination
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| specificity; | — |
Secondary
| Measure | Time frame |
|---|---|
| sensitivity;accuracy;positive predictive value;negative predictive value;area under the curve; | — |
Countries
P.R. China
Contacts
Public ContactBo-wen Zheng
the Third Affiliated Hospital of Sun Yat-sen University
Outcome results
None listed