colorectal cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1)ASA?~? grade; 2) Patients undergoing radical resection for colorectal cancer; 3) Can communicate normally; 4) Age 65-80 years old; 5) Agree to participate in the study and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1) A history of brain disease; 2)MiniCog score =1 score; 3) History of neurological and psychological diseases such as stroke and psychosis; 4) Severe hearing or visual impairment; 5) Severe liver or kidney failure or heart failure (New York College of Cardiology =III; 6) The patient or family member refuses.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| POD occurrence 7 days after surgery;Perioperative intestinal flora distribution in two groups; | — |
Secondary
| Measure | Time frame |
|---|---|
| Severity, duration, and subtype of delirium;hospital stays;30-day all-cause mortality;The occurrence of adverse events; | — |
Countries
China
Contacts
The Fourth Hospital of Hebei Medical University