Secondary infection caused by antibiotics in critically ill patients
Conditions
Sponsors
Wuxi No.2 People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: ?=18 years old; ? patients meet the specific diagnostic criteria for acute and severe diseases, such as septic shock, severe pneumonia, etc.; ? patients who have received antibiotics; ? Clinical symptoms and signs of double infection, such as fever and abnormal white blood cell count; ?volunteer to participate in the study; ? conscious; ? They can communicate with each other normally.
Exclusion criteria
Exclusion criteria: ? Suffering from severe cardiovascular and cerebrovascular diseases, respiratory system diseases, immune system diseases and severe liver and kidney damage; ? suffering from severe mental illness, such as depression, generalized anxiety disorder, etc.; ? The patient's current condition is not suitable for colonoscopy; ? patients with allergic reactions to gut microbiota transplantation; ? patients who fail to provide complete medical history or examination data; ? For various reasons, this study could not be performed and various tests were needed.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood routine and rapid CRP;blood culture;procalcitonin;routine urine test;stool for routine;drug sensitive test;Amplification quantitative culture;mass spectrum identification;16S rRNA sequencing;Basic data of patients; | — |
Secondary
| Measure | Time frame |
|---|---|
| liver function;renal function; | — |
Countries
China
Contacts
Public ContactFeng Ninghan
Wuxi No.2 People's Hospital
Outcome results
None listed