Parkinson's disease
Conditions
Interventions
none:none
Sponsors
Peking University Shenzhen Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: ? Age 50-80 years old (inclusive); ? Meet the diagnosis of Parkinson's disease according to the diagnostic criteria of the British Brain Bank or the diagnostic criteria of MDS 2018 "Clinically Confirmed Parkinson's Disease"; ?Anti-Parkinson's drugs were not adjusted for more than 6 months after treatment with levodopa and nearly 4 weeks after treatment; ? Right-handed.
Exclusion criteria
Exclusion criteria: ?The presence of other diseases that may affect the structure or function of the brain (history of head trauma, severe brain atrophy, stroke, brain tumor, epilepsy, schizophrenia, delirium, mania, dementia, severe liver disease, kidney disease, etc.); ? There is a history of drug abuse, alcoholism, nicotine addiction; ? has been complicated by transactivity; ?There are contraindications for PET-MRI (metal implants, pacemakers, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Positron Emission Computed Tomography Imaging;Magnetic resonance imaging; | — |
Secondary
| Measure | Time frame |
|---|---|
| Unified Parkinson's Disease Rating Scale,UPDRS; | — |
Countries
China
Contacts
Public ContactQiaoling Zeng
Peking University Shenzhen Hospital
Outcome results
None listed