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The regulatory function of the inhaled asthma medication Salbutamol on thermogenesis

The regulatory function of the inhaled asthma medication Salbutamol on thermogenesis

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400083734
Enrollment
Unknown
Registered
2024-04-30
Start date
2024-05-01
Completion date
Unknown
Last updated
2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity

Interventions

Male:The subjects were requested to follow a similar daily schedule, including time of meals, rest/active hours and amounts of exercises, and avoid vigorous exercise, caffeine, drugs or alcohol consum
Female:The subjects were requested to follow a similar daily schedule, including time of meals, rest/active hours and amounts of exercises, and avoid vigorous exercise, caffeine, drugs or alcohol cons

Sponsors

Tongji University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
23 Years to 30 Years

Inclusion criteria

Inclusion criteria: 1. Aged 20-40 years, with at least 10 males and 10 females; 2. After administering the drug, the heart rate, blood pressure, and blood components of the subjects will be tested; 3. No history of asthma or diagnosed with bronchial asthma according to the "Chinese Guidelines for the Prevention and Treatment of Bronchial Asthma (2016 Edition)," and currently still in the persistent phase; 4. During the lead-in period and treatment period of the study, able to discontinue the study drug and other beta-receptor agonist medications used for treating asthma (such as inhaled long-acting beta-receptor agonists); 5. Subjects who agree to participate in this clinical trial and sign a written informed consent form.

Exclusion criteria

Exclusion criteria: 1. Subjects with clinically significant major pulmonary diseases; 2. Subjects with other diseases associated with elevated eosinophil counts; 3. Individuals allergic to Salbutamol; 4. Individuals allergic to fluorocarbons used as propellants; 5. Patients with cardiovascular dysfunction, insufficient coronary artery supply, hypertension, diabetes, and hyperthyroidism; 6. Individuals allergic to other adrenergic receptor agonists; 7. Women who are pregnant, breastfeeding, or planning to become pregnant in the near future; 8.Individuals with rare hereditary digestive system diseases - lactose intolerance, lactase deficiency, or glucose-galactose malabsorption; 9.Other reasons deemed by the researcher as inappropriate for participation in the trial.

Design outcomes

Primary

MeasureTime frame
Thermal signatures of supraclavicular depots ;

Secondary

MeasureTime frame
Heart rate;Blood pressure;Blood components;

Countries

China

Contacts

Public ContactBing Luan

Tongji University

bluan@tongji.edu.cn+86 132 6282 5126

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026