depression with psychotic symptoms
Conditions
Interventions
Experimental group:Sertraline and quetiapine plus value-oriented short-term psychotherapy
Control group psychotherapy:Sertraline and quetiapine
Sponsors
The Second Affiliated Hospital of Xinxiang Medical College
Eligibility
Sex/Gender
All
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: (1) Sign the informed consent; (2) Meet the DSM-5 diagnostic criteria for depression with psychotic symptoms; (3) Scale score standard: Hamilton Depression Scale (HAMD) (24 items) =17 points; (4) PANSS positive scale score =15 points; (5) Age 18-45 years old; (6) Did not take antidepressant or antipsychotic drugs other than sertraline and quetiapine within 1 week before enrollment; (7) Normal intelligence, junior high school or above education level; (8) Right hand.
Exclusion criteria
Exclusion criteria: (1) Persons suffering from other major diseases, head trauma, cardiovascular diseases, loss of consciousness or mental disorders; (2) Drug, drug or alcohol abusers; (3) Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hamilton Depression Scal;Hamilton Anxiety Scale;Hamilton Depression Scal;Hamilton Anxiety Scal;Positive and Negative Syndrome; | — |
Countries
China
Contacts
Public ContactChangHong Wang
The Second Affiliated Hospital of Xinxiang Medical College
Outcome results
None listed