subarachnoid hemorrhage, traumatic brain injury, cerebral hemorrhage
Conditions
Interventions
liberal transfusion strategy group:Patients in the liberal transfusion strategy group will not receive an allogeneic RBC transfusion when hemoglobin is over 90 g/L after IAT. Patients will receive an
restrictive transfusion strategy group:Patients in the restrictive transfusion strategy group will not receive an allogeneic RBC transfusion when hemoglobin is over 70 g/L after IAT. Patients will rec
Sponsors
Beijing Tiantan Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) 18 years=age=65 years (2) proposed craniotomy hematoma removal for acute brain injury (traumatic brain injury/subarachnoid hemorrhage/cerebral hemorrhage) (3) hemoglobin concentrations below 90 g/L (4) signed informed consent
Exclusion criteria
Exclusion criteria: (1) life-threatening patients in need of emergency treatment (2) patients with severe heart disease (3) pregnant or lactating women (4) patients who have already received a red blood cell infusion before surgery (5) patients who refuse transfusion (6) patients with Glasgow outcome scale=3, patients with dilated and fixed pupils (7) patients with clinically diagnosed brain death
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| GOSe score at discharge; | — |
Secondary
| Measure | Time frame |
|---|---|
| GOS-E score at 6 months postoperatively;Mortality in hospitals;Transfusion-related adverse reactions;Systemic complications;Length of stay in ICU; | — |
Countries
China
Contacts
Public ContactYu Yun
Beijing Tiantan Hospital Affiliated to Capital Medical University
Outcome results
None listed