Allergic conjunctivitis
Conditions
Interventions
Two:Antihistamines
Sponsors
Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong
Eligibility
Sex/Gender
All
Age
12 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1) Sign the informed consent form and comply with the study regulations. 2) More than or equal to 12 years old, regardless of gender; (Both minor patients and guardians need to sign the informed consent form) 3) Tear samples taken before randomization were tested for IgE. 4) A diagnosis of seasonal allergic conjunctivitis (seasonal onset, recent consecutive episodes more than 1 month), involving both eyes; 5) No use of relevant anti-allergic and hormone drugs in the past 2 weeks or difficult to control with such drugs (if there are relevant drugs, normal saline washout for 1 week after enrollment) 6) Assessment of symptoms and signs should meet at least the following: a) A self-rated score of at least 2 for eye itching; b) A score of at least 1 or higher in mild conjunctival congestion assessor;
Exclusion criteria
Exclusion criteria: 1) patients with recent eye infection, bleeding or other local diseases, and topical use of anti-allergic or hormone drugs; 2) patients with ocular pterygium, scar, trichiasis, periocular acne, eyelid dysclosure, eyelid entropion, tumor and other ocular surface structures; 3) patients with a history of ocular local surgery; Women in pregnancy; Wearing contact lenses; 4) patients with or suspected of glaucoma, or with a history of any progressive retinal disease such as retinal detachment; 5) conjunctival inflammatory hyperplastic changes in the past 2 years, including giant papillary hyperplasia and cobblestone changes; 5) patients with major chronic diseases including but not limited to patients with cardiopulmonary diseases, diabetes, mental disorders, etc.; 6) best corrected visual acuity (BCVA) less than 4.4 on a five-point scale at screening; 7) intraocular pressure > 21 mmHg or < 8 mmHg at screening 8) ocular trauma within 3 months before screening (except those judged by the investigator to have no effect on the efficacy and safety results of the study) 9) patients with known photoallergy or emmetin allergy. 10) There were other factors considered by the investigators to be unsuitable for participation in this study, including those who were unable or unwilling to follow the protocol.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Subjective visual analogue scale (VAS) of symptoms; | — |
Secondary
| Measure | Time frame |
|---|---|
| Red eye analysis; | — |
Countries
China
Contacts
Public ContactLi Dan
Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong
Outcome results
None listed