osteoarthritis
Conditions
Interventions
LIA+ACB group:knee infiltration of bupivacaine liposome with ultrasound-guided adductor canal block
FNB group:ultrasound-guided femoral nerve block
Sponsors
The Fourth Affiliated Hospital of Nanjing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Adult patients of ASA I and II, who are scheduled to undergo total knee arthroplasty under spinal anaesthetic.
Exclusion criteria
Exclusion criteria: 1) BMI>40kg/m^2; 2) inability to obtain informed consent due to cognitive dysfunction or abnormal mental state; 3) renal and hepatic disease; 4) known allergies to local anesthetics; 5) infection at the site of block; 6) a history of postoperative nausea and vomiting; 8) lower limb neuropathy or movement disorder; 8) a history of long-term use of opioids; 9) coagulopathy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| analgesic consumption; | — |
Secondary
| Measure | Time frame |
|---|---|
| pain score;time up and go test;quadriceps strength ;knee range of motion;incidence of postoperative nausea and vomiting;incidence of adverse events of nerve block; | — |
Countries
China
Contacts
Public ContactHu Yuping
The Fourth Affiliated Hospital of Nanjing Medical University
Outcome results
None listed