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Efficacy and safety of nasal high-flow oxygen therapy in maintaining oxygenation during induction of general anesthesia in obese parturients

Efficacy and safety of nasal high-flow oxygen therapy in maintaining oxygenation during induction of general anesthesia in obese parturients

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400083682
Enrollment
Unknown
Registered
2024-04-30
Start date
2024-05-01
Completion date
Unknown
Last updated
2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cesarean section

Interventions

Control group(standard facemask group,SFM group):All pregnant women were given a 10L/min flow of pure oxygen for 3 minutes using a mask, and the anesthesiologist held the mask to ensure good sealing w
Experimental group(High-flow nasal oxygenation,HFNO group):All pregnant women were given nasal high-flow oxygen inhalation at 10L/min after entering the room, and the oxygen flow was adjusted to 30L/m

Sponsors

Department of Anesthesiology, the Affiliated Yantai Yuhuangding Hospital of Qindao University
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Patients undergoing general anesthesia for cesarean section, ASA classification I-III, aged 20-40 years, BMI >30kg/m2.

Exclusion criteria

Exclusion criteria: 1. Refusal of the parturient 2. Risk of hemorrhagic shock during the operation 3. Combined hepatic and renal insufficiency 4. Coagulopathy 5. Combined mental illness

Design outcomes

Primary

MeasureTime frame
Arterial partial pressure of oxygen, partial pressure of carbon dioxide, and end-tidal partial pressure of carbon dioxide at the end of induced ventilation;record the blood gas analysis of fetal umbilical artery and umbilical vein after delivery;Apar scores at 1 minute and 5 minutes after delivery of the fetus;patient comfort during maternal pre-oxygenation;

Secondary

MeasureTime frame
the incidence of adverse events such as postoperative gastric bloating, nausea and vomiting, reflux aspiration, nasopharyngeal discomfort, and barotrauma in maternal patients;

Countries

China

Contacts

Public ContactMa Jiahai

Department of Anesthesiology, the Affiliated Yantai Yuhuangding Hospital of Qindao University

mjh-214@163.com+86 136 5645 6186

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026