Blood purification
Conditions
Interventions
Experimental group:Plasma transfusion after DFPP treatment
Control group:Supplementing plasma during DFPP treatment
Sponsors
Shanghai East Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1: Requiring DFPP treatment for any reason 2: Requiring the use of Cascadeflo EC 20W as a secondary plasma separator due to clinical necessity 3: No severe organic or psychiatric disorders 4: Patients who understand and are willing to cooperate with this study and consent to participate by signing an informed consent form
Exclusion criteria
Exclusion criteria: 1: Age less than 18 years or older than 80 years 2: Pregnant or lactating 3: Presence of contraindications to heparin 4: Presence of thrombocytopenia (PLT < 100 * 10^9/L) 5: Presence of significant bleeding risk 6: Severe liver dysfunction 7: Inability to establish suitable vascular access 8: Refractory shock 9: End-stage malignant tumors 10: Expected survival time < 48 hours 11: Lack of legal capacity
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Coagulation factor activity; | — |
Secondary
| Measure | Time frame |
|---|---|
| APTT;PT;INR;Platelets; | — |
Countries
China
Contacts
Public ContactZhang Yunhe
Shanghai East Hospital
Outcome results
None listed